Synonyms: LM 427 | Mycobutin® | Rifabutine
rifabutin is an approved drug (FDA (1992), UK (2003))
Compound class:
Synthetic organic
Comment: Rifabutin is a derivative of rifamycin S and belongs to the ansamycin group of antibacterial compounds [1]. It is on the World Health Organization's Model List of Essential Medicines (link provided in the Classification table, under the Summary tab below) for use as an oral antituberculosis medication.
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References |
1. Della Bruna C, Schioppacassi G, Ungheri D, Jabès D, Morvillo E, Sanfilippo A. (1983)
LM 427, a new spiropiperidylrifamycin: in vitro and in vivo studies. J Antibiot (Tokyo), 36 (11): 1502-6. [PMID:6317622] |
2. Woodley CL, Kilburn JO. (1982)
In vitro susceptibility of Mycobacterium avium complex and Mycobacterium tuberculosis strains to a spiro-piperidyl rifamycin. Am Rev Respir Dis, 126 (3): 586-7. [PMID:6289711] |