WRWWWW   Click here for help

GtoPdb Ligand ID: 1040

Synonyms: WRW4
Immunopharmacology Ligand
Comment: Selective FPR2 antagonist peptide.
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1. Bae YS, Lee HY, Jo EJ, Kim JI, Kang HK, Ye RD, Kwak JY, Ryu SH. (2004)
Identification of peptides that antagonize formyl peptide receptor-like 1-mediated signaling.
J Immunol, 173 (1): 607-14. [PMID:15210823]
2. Bozinovski S, Anthony D, Anderson GP, Irving LB, Levy BD, Vlahos R. (2013)
Treating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways.
Pharmacol Ther, 140 (3): 280-9. [PMID:23880288]
3. Shin EH, Lee HY, Kim SD, Jo SH, Kim MK, Park KS, Lee H, Bae YS. (2006)
Trp-Arg-Trp-Trp-Trp-Trp antagonizes formyl peptide receptor like 2-mediated signaling.
Biochem Biophys Res Commun, 341 (4): 1317-22. [PMID:16476585]
4. Stama ML, Lacivita E, Kirpotina LN, Niso M, Perrone R, Schepetkin IA, Quinn MT, Leopoldo M. (2017)
Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress.
ChemMedChem, 12 (22): 1839-1847. [PMID:28922577]