Compound class:
Synthetic organic
Comment: RU1968 is a cross-species inhibitor of CatSper Ca2+ channels [1]. It can be used as a chemical probe to elucidate the function of CatSper channels in sperm from different species.
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References |
1. Rennhack A, Schiffer C, Brenker C, Fridman D, Nitao ET, Cheng YM, Tamburrino L, Balbach M, Stölting G, Berger TK et al.. (2018)
A novel cross-species inhibitor to study the function of CatSper Ca2+ channels in sperm. Br J Pharmacol, 175 (15): 3144-3161. [PMID:29723408] |