dostarlimab

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dostarlimab

GtoPdb Ligand ID: 11518

Synonyms: ANB-011 | dostarlimab-gxly | Jemperli® | TSR-042 | WBP-285

dostarlimab is an approved drug (EMA & FDA (2021))

Comment: Dostarlimab is a humanized, IgG4κ programmed cell death 1 (PD-1) blocking monoclonal antibody from GlaxoSmithKline.

Summary
Biological activity
Clinical data
References
Immunopharmacology

Immunopharmacology Comments
Dostarlimab blocks the inhibitory immune checkpoint interaction between PD-1 and its ligands PD-L1 and PD-L2 to promote an antitumour T-cell response.

Immunopharmacology Comments

Dostarlimab blocks the inhibitory immune checkpoint interaction between PD-1 and its ligands PD-L1 and PD-L2 to promote an antitumour T-cell response.