atibuclimab   Click here for help

GtoPdb Ligand ID: 11326

Synonyms: IC14
Immunopharmacology Ligand
Compound class: Antibody
Comment: Atibuclimab (IC14) is a monoclonal antibody against CD14 [1]. It was developed by ICOS Corporation (acquired by Eli Lilly) and is being progressed in COVID-19 by Implicit Bioscience.
Immunopharmacology Comments
In relation to sepsis, targeting CD14 inhibits endotoxin-mediated symptoms and inflammatory responses in humans [3,5-6].