Synonyms: 506U78 | Arranon® | Atriance®
nelarabine is an approved drug (FDA (2005), EMA (2007))
Compound class:
Synthetic organic
Comment: This compound is a prodrug. The active metabolite is its 5'-triphosphate, ara-GTP.
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No information available. |
Mechanism Of Action and Pharmacodynamic Effects ![]() |
The incorporation of the active compound metabolised from nelarabine, inhibits DNA synthesis and causes cell death. |
External links ![]() |
For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com European Medicines Agency (EMA) |