Ligand id: 8420

Name: UK-432,097

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 16
Hydrogen bond donors 7
Rotatable bonds 18
Topological polar surface area 220.78
Molecular weight 777.37
XLogP 4
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
A2A receptor Hs Agonist Agonist 7.7 – 8.3 pKi - 1-2
pKi 7.7 – 8.3 [1-2]