UK-432,097

Ligand id: 8420

Name: UK-432,097

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 16
Hydrogen bond donors 7
Rotatable bonds 18
Topological polar surface area 220.78
Molecular weight 777.37
XLogP 4
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
A2A receptor Hs Agonist Agonist 7.7 – 8.3 pKi - 1-2
pKi 7.7 – 8.3 [1-2]