canakinumab   Click here for help

GtoPdb Ligand ID: 6773

Synonyms: ACZ 885 | ACZ885 | Ilaris®
Approved drug Immunopharmacology Ligand
canakinumab is an approved drug (FDA (2009), EMA (2009))
Compound class: Antibody
Comment: Canakinumab targets interleukin-1β [1].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
IL-1β Primary target of this compound Hs Antibody Binding 10.5 pKd - 3
⤷ pKd 10.5 (Kd 3.5x10-11 M) [3]