Synonyms: AG-1295 | AG1295
Compound class:
Synthetic organic
Comment: AG 1295 is a cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor receptor (PDGFR) tyrosine kinase [3].
|
|
Bioactivity Comments |
AG 1295 inhibits in vitro autophosphorylation of mouse PDGFR with an IC50 of 300-500nM [3]. |