[125I]-HPP-icatibant   Click here for help

GtoPdb Ligand ID: 11158

Synonyms: [(125)I]-HPP-Hoe 140 | [125I]3-4 hydroxyphenyl-propionyl-D-Arg[Hyp3, Thi5, D-Tic7, Oic8]-BK | [125I]3-4 hydroxyphenyl-propionyl-D-Arg[Hyp3, Thi5, D-Tic7, Oic8]-bradykinin | [125I]3-4 hydroxyphenyl-propionyl-icatibant
 Ligand is labelled  Ligand is radioactive
Comment: This is a radiolabelled analogue of the B2 receptor antagonist icatibant [1-2]. It can be used for receptor autoradiography and radioligand binding assays.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
B2 receptor Rn Antagonist Antagonist 10.5 pKd - 1
pKd 10.5 (Kd 3x10-11 M) [1]