SKF-82958   Click here for help

GtoPdb Ligand ID: 10742

Synonyms: SKF 82958 | SKF82958
Compound class: Synthetic organic
Comment: Dopamine D1 receptor agonist. SKF-82958 hydrobromide is a D1/D5 receptor full agonist.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 43.7
Molecular weight 329.12
XLogP 3.85
No. Lipinski's rules broken 0
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Canonical SMILES C=CCN1CCc2c(C(C1)c1ccccc1)cc(c(c2Cl)O)O
Isomeric SMILES C=CCN1CCc2c(C(C1)c1ccccc1)cc(c(c2Cl)O)O
InChI InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
D1 receptor Hs Agonist Agonist - - - 1