α-linolenic acid

Ligand id: 1049

Name: α-linolenic acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 13
Topological polar surface area 37.3
Molecular weight 278.22
XLogP 7.54
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
FFA1 receptor
FFA4 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
FFA4 receptor Hs Agonist Full agonist 5.5 pEC50 - 6
pEC50 5.5 [6]
FFA1 receptor Hs Agonist Full agonist 4.6 – 5.7 pEC50 - 1-3
pEC50 4.6 – 5.7 [1-3]
FFA4 receptor Rn Agonist Full agonist 5.1 pEC50 - 7
pEC50 5.1 [7]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields