Fz7-21   Click here for help

GtoPdb Ligand ID: 10324

Comment: Fz7-21 is a peptide antagonist of FZD7 [1]. It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
FZD7 Hs Antagonist Antagonist 7.0 pIC50 - 1
pIC50 7.0 (IC50 1x10-7 M) [1]
Description: In a TOPbrite dual-luciferase reporter assay.