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Xilonix TN   Click here for help

GtoPdb Ligand ID: 8528

Immunopharmacology Ligand
Compound class: Antibody
Comment: Xilonix is an investigational fully human monoclonal antibody targeting IL-1α. A patent search suggest that Xilonix is the subject of WO2009148575 [1], although we do not have access to the peptide sequences of the antibody to confirm this.
Immunopharmacology Comments
Xilonix is included in GtoImmuPdb as an immuno-oncology agent. The rationale for using anti-IL-1α antibodies to treat cancer is provided in patent US20100040574 [2].