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tralokinumab is an approved drug (EMA & FDA (2021))
Compound class:
Antibody
Comment: Tralokinumab is a monoclonal antibody directed against interleukin 13 (IL-13), a cytokine secreted by T helper cells, and which is a central mediator of the physiological changes induced by allergic inflammatory reactions [4] Binding affinity of tralokinumab was optimised (aka affinity maturation) using an in vitro ribosome display technology [2].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. |
Classification ![]() |
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| Compound class | Antibody |
| Approved drug? | Yes. EU EMA (2021) | US FDA (2021) |
International Nonproprietary Names ![]() |
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| INN number | INN |
| 9235 | tralokinumab |
Synonyms ![]() |
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| Adbry® | Adtralza® | BAK1.1 [2] | CAT-354 [2] | tralokinumab-ldrm | |
Database Links ![]() |
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| Specialist databases | |
| IMGT/mAb-DB | 171 |
| Other databases | |
| GtoPdb PubChem SID | 249565681 |
| Search PubMed clinical trials | tralokinumab |
| Search PubMed titles | tralokinumab |
| Search PubMed titles/abstracts | tralokinumab |
| Wikipedia | Tralokinumab |