Synonyms: AZ 11920155 | AZ-11920155 | AZ11920155 | AZD 6605 | AZD-6605
Compound class:
Synthetic organic
Comment: AZD6605 is a potent, reversible inhibitor of matrix metalloproteinases MMP13 (Collagenase 3), MMP2, MMP9 and MMP12. The discovery of this compound is described in [1], where it is compound 3m.
This compound was in the AstraZeneca/MRC repurposing list from 2011. Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
(5S)-5-methyl-5-[[4-[4-(1,1,2,2-tetrafluoroethoxy)phenoxy]piperidin-1-yl]sulfonylmethyl]imidazolidine-2,4-dione |
Synonyms |
AZ 11920155 | AZ-11920155 | AZ11920155 | AZD 6605 | AZD-6605 |
Database Links | |
ChEMBL Ligand | CHEMBL2409707 |
GtoPdb PubChem SID | 223366154 |
PubChem CID | 11641563 |
Search Google for chemical match using the InChIKey | SBVAXUGOISPYPX-QGZVFWFLSA-N |
Search Google for chemicals with the same backbone | SBVAXUGOISPYPX |
UniChem Compound Search for chemical match using the InChIKey | SBVAXUGOISPYPX-QGZVFWFLSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | SBVAXUGOISPYPX-QGZVFWFLSA-N |