GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.
| 
                               
                            
                                
                                                                Synonyms: Nucala® | SB-240563
                                 
                                                         
                            
                            
                            
                                 
                                
                                mepolizumab is an approved drug (EMA & FDA (2015)) 
                                                        
                                                    
                                Compound class: 
                                                            Antibody
                                 
                                
                                    
                                        Comment: The Nucala® brand of mepolizumab is a humanized interleukin-5 antagonist monoclonal antibody produced by recombinant DNA technology in Chinese hamster ovary cells.
                                    
                                 
                            
                            
                          
                                
                                    
                                
                          
                                View more information in the IUPHAR Pharmacology Education Project: mepolizumab  | 
                                    
Classification ![]()  | 
                                                    |
| Compound class | Antibody | 
| Approved drug? | Yes. China NMPA (2024) | US FDA (2015) | EU EMA (2015) | 
International Nonproprietary Names ![]()  | 
                                                        |
| INN number | INN | 
| 7876 | mepolizumab | 
Synonyms ![]()  | 
                                                        
| Nucala® | SB-240563 | 
Database Links ![]()  | 
                                                        |
| Specialist databases | |
| IMGT/mAb-DB | 87 | 
| Other databases | |
| GtoPdb PubChem SID | 223366020 | 
| Search PubMed clinical trials | mepolizumab | 
| Search PubMed titles | mepolizumab | 
| Search PubMed titles/abstracts | mepolizumab | 
| Wikipedia | Mepolizumab |