carphenazine   Click here for help

GtoPdb Ligand ID: 7140

Synonyms: Proketazine® | WY-2445
Approved drug
carphenazine is an approved drug
Compound class: Synthetic organic
Comment: Carphenazine is an antipsychotic drug. There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation. The Electronic Medicines Compendium (eMC) lists buclizine only as an active ingredient in a multi-component, anti-migraine treatment alongside paracetamol and codeine.
Marketed formulations may contain carphenazine maleate (PubChem CID 20838085).
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 72.32
Molecular weight 425.21
XLogP 3.37
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(=O)CC
Isomeric SMILES OCCN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(=O)CC
InChI InChI=1S/C24H31N3O2S/c1-2-22(29)19-8-9-24-21(18-19)27(20-6-3-4-7-23(20)30-24)11-5-10-25-12-14-26(15-13-25)16-17-28/h3-4,6-9,18,28H,2,5,10-17H2,1H3
InChI Key XZSMZRXAEFNJCU-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)propan-1-one
International Nonproprietary Names Click here for help
INN number INN
1179 carfenazine
Synonyms Click here for help
Proketazine® | WY-2445
Database Links Click here for help
CAS Registry No. 2622-30-2
ChEMBL Ligand CHEMBL1201328
DrugBank Ligand DB01038
DrugCentral Ligand 516
GtoPdb PubChem SID 178103716
PubChem CID 18104
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Wikipedia Carfenazine