Synonyms: Vonvendi® | vWF
von Willebrand factor is an approved drug (FDA (2015))
Comment: Details of the structure of von Willebrand factor (vWF) are available in its UniProt record. The pre-pro peptide is 2813 amino acids, with residues 1-22 being the signal peptide, residues 23-763 forming von Willebrand antigen 2, and the remaining 2050 residues (764-2813) constituting vWF. The Uniprot record also provides details of mutations underlying defective vWF activity in the three subtypes of von Willebrand disease.