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IL-17F   Click here for help

GtoPdb Ligand ID: 5873

Synonyms: cytokine ML-1 | Interleukin-17F
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: Forms homodimeric ligand IL-17F and heterodimer IL-17A/IL-17F with IL-17A.
Species: Human
Is a component of
IL-17A/IL-17F
Peptide Sequence Click here for help
RKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA
QGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
Arg-Lys-Ile-Pro-Lys-Val-Gly-His-Thr-Phe-Phe-Gln-Lys-Pro-Glu-Ser-Cys-Pro-Pro-Val-Pro-Gly-Gly-Ser-Met-Lys-Leu-Asp-Ile-Gly-Ile-Ile-Asn-Glu-Asn-Gln-Arg-Val-Ser-Met-Ser-Arg-Asn-Ile-Glu-Ser-Arg-Ser-Thr-Ser-Pro-Trp-Asn-Tyr-Thr-Val-Thr-Trp-Asp-Pro-Asn-Arg-Tyr-Pro-Ser-Glu-Val-Val-Gln-Ala-Gln-Cys-Arg-Asn-Leu-Gly-Cys-Ile-Asn-Ala-Gln-Gly-Lys-Glu-Asp-Ile-Ser-Met-Asn-Ser-Val-Pro-Ile-Gln-Gln-Glu-Thr-Leu-Val-Val-Arg-Arg-Lys-His-Gln-Gly-Cys-Ser-Val-Ser-Phe-Gln-Leu-Glu-Lys-Val-Leu-Val-Thr-Val-Gly-Cys-Thr-Cys-Val-Thr-Pro-Val-Ile-His-His-Val-Gln
Post-translational Modification
N-linked glycosylation of asparagine residue at position 53; disulphide bonds between cysteine residues at positions 72 and 122, and 77 and 124; interchain disulphide bonds in formation of the heterodimer at positions 17 and 107.