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Synonyms: Thyrogen® | thyroid-stimulating hormone | thyrotropin
TSH is an approved drug (FDA (1953))
Compound class:
Endogenous peptide in human, mouse or rat
Comment: The drug thyrotropin alfa is a peptide heterodimer consisting of an α and β subunit and mimics the endogenous peptide hormone.
Species: Human
View more information in the IUPHAR Pharmacology Education Project: tsh |
| Subunits |
| TSH β subunit |
| glycoprotein hormone common alpha subunit |
Peptide Sequence ![]() |
| No information available. |
| Post-translational Modification | |
| The production of biologically active TSH requires appropriately folded TSHβ and common α subunits that assemble to form the TSH heterodimer. | |