α-MSH   Click here for help

GtoPdb Ligand ID: 1320

Synonyms: α-melanocyte stimulating hormone
Compound class: Endogenous peptide in human, mouse or rat
Species: Human, Mouse, Rat
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

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View more information in the IUPHAR Pharmacology Education Project: msh

Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Synonyms Click here for help
α-melanocyte stimulating hormone
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
POMC proopiomelanocortin Human pro-opiomelanocortin ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte stimulating hormone, beta-endorphin, beta-lipotropin, beta-melanocyte stimulating hormone, CLIP, LPH, MSH, NPP, POC
Pomc pro-opiomelanocortin-alpha Mouse pro-opiomelanocortin ACTH, adrenal corticotropic hormone, alpha-melanocyte stimulating hormone, alpha-MSH, alphaMSH, BE, beta-endorphin, beta-melanocyte stimulating hormone, beta-MSH, gamma-melanocyte stimulating hormone, gamma-MSH, POMC, Pomc-1
Pomc proopiomelanocortin Rat pro-opiomelanocortin alpha-melanocyte-stimulating hormone, alphaMSH, corticotropin-lipotropin, Pomc1, Pomc2, pro-opiomelanocortin, proopiomelanocortin, proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin), pro-opiomelanocortin-alpha, proopiomelanocortin, beta (endorphin, beta), proopoimelanocortin, beta (endorphin, beta)
Database Links Click here for help
Specialist databases
GPCRdb Ligand alpha-MSH
Other databases
CAS Registry No. 581-05-5
Ensembl Gene ENSG00000115138 (Hs), ENSMUSG00000020660 (Mm)
GtoPdb PubChem SID 135651610
Human Protein Atlas ENSG00000115138 (Hs)
PubChem CID 16162729
UniProtKB P01194 (Rn), P01193 (Mm), P01189 (Hs)