loncastuximab tesirine   Click here for help

GtoPdb Ligand ID: 11521

Synonyms: ADCT-402 | ADCT402 | loncastuximab tesirine-lpyl | RB4v1.2-SG-3249 | Zynlonta®
Approved drug
loncastuximab tesirine is an approved drug (FDA (2021), EMA (2022))
Compound class: Antibody
Comment: Loncastuximab tesirine (ADCT-402) is an antibody-drug conjugate that delivers the toxic payload teserine (pyrrolobenzodiazepine dimer SG3249, which acts as a DNA alkylating and cross-linking agent [3]) to CD19-expressing B cells [4].
Classification Click here for help
Compound class Antibody
Approved drug? Yes (FDA (2021), EMA (2022))
International Nonproprietary Names Click here for help
INN number INN
10586 loncastuximab tesirine
Synonyms Click here for help
ADCT-402 | ADCT402 | loncastuximab tesirine-lpyl | RB4v1.2-SG-3249 | Zynlonta®
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 749
Other databases
GtoPdb PubChem SID 441604893
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