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                                                                Synonyms: PRO 140 | PRO-140 | PRO140 | Vyrologix®
                                 Compound class: 
                                                            Antibody
                                 
                                    
                                        Comment: Leronlimab (PRO140) is a humanized anti-CCR5 (C-C motif chemokine receptor 5) monoclonal antibody [5-6]. It was originally developed by CytoDyn as a novel strategy to manage CCR5-tropic HIV infection [4]. SARS-CoV-2 and COVID-19: Leronlimab has been administered to a number of patients with severe COVID-19, to determine its potential to reduce cytokine storm caused by this disease. | 
| Classification  | |
| Compound class | Antibody | 
| International Nonproprietary Names  | |
| INN number | INN | 
| 10751 | leronlimab | 
| Synonyms  | 
| PRO 140 | PRO-140 | PRO140 | Vyrologix® | 
| Database Links  | |
| Specialist databases | |
| GPCRdb Ligand | leronlimab | 
| IMGT/mAb-DB | 807 | 
| Other databases | |
| GtoPdb PubChem SID | 405560193 | 
| Search PubMed clinical trials | leronlimab | 
| Search PubMed titles | leronlimab | 
| Search PubMed titles/abstracts | leronlimab |