compound 15 [PMID: 29852070] [Ligand Id: 9997] activity data from GtoPdb

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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
GtoPdb In a biochemical enzyme activity assay. - 5.1 pIC50 7943 nM IC50 J Med Chem (2018) 61: 5435-5441 [PMID:29852070]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
GtoPdb In a biochemical enzyme activity assay. - 4.5 pIC50 >31600 nM IC50 J Med Chem (2018) 61: 5435-5441 [PMID:29852070]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
GtoPdb In a biochemical enzyme activity assay. - 6.5 pIC50 316 nM IC50 J Med Chem (2018) 61: 5435-5441 [PMID:29852070]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
GtoPdb In a biochemical enzyme activity assay. - 9.1 pIC50 0.79 nM IC50 J Med Chem (2018) 61: 5435-5441 [PMID:29852070]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.