apilimod [Ligand Id: 9859] activity data from GtoPdb

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  • phosphoinositide kinase, FYVE-type zinc finger containing in Human [GtoPdb: 2857] [UniProtKB: Q9Y2I7]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphoinositide kinase, FYVE-type zinc finger containing in Human [GtoPdb: 2857] [UniProtKB: Q9Y2I7]
GtoPdb Binding constant for Cy5-apilimod to PIKfyve kinase domain. - 7.19 pKd 65 nM Kd Chem. Biol. (2013) 20: 912-21 [PMID:23890009]
GtoPdb Effect of apilimod on hPIKfyve kinase activity in vitro measuringPI(3)P conversion to PI(3,5)P2. - 7.85 pIC50 14 nM IC50 Chem. Biol. (2013) 20: 912-21 [PMID:23890009]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.