compound 36 [PMID: 21958547] [Ligand Id: 9391] activity data from GtoPdb

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  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
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  • LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
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  • LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
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  • SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb - - 8.71 pIC50 1.93 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
GtoPdb - - 6.11 pIC50 772 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
GtoPdb - - 6.2 pIC50 624 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
GtoPdb - - 6.53 pIC50 298 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.