compound 36 [PMID: 21958547] [Ligand Id: 9391] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 Bruton tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
  • LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 LCK proto-oncogene, Src family tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
  • LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 LYN proto-oncogene, Src family tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
  • SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 SRC proto-oncogene, non-receptor tyrosine kinase Human
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb - - 8.71 pIC50 1.93 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
GtoPdb - - 6.11 pIC50 772 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
GtoPdb - - 6.2 pIC50 624 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]
SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
GtoPdb - - 6.53 pIC50 298 nM IC50 Bioorg Med Chem Lett (2011) 21: 6258-63 [PMID:21958547]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.