CDP840 [Ligand Id: 9330] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL32442 |
|---|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| phosphodiesterase 4A in Human [GtoPdb: 1300] [UniProtKB: P27815] | ||||||||
| GtoPdb | Inhibition of [3H]-R-rolipram binding to recombinant human PDE-4 isoenzyme | - | 8.01 | pKi | 9.7 | nM | Ki | Cell Biochem Biophys (1998) 29: 113-32 [PMID:9631241] |
| phosphodiesterase 4B in Human [GtoPdb: 1301] [UniProtKB: Q07343] | ||||||||
| GtoPdb | Inhibition of [3H]-R-rolipram binding to recombinant human PDE4B2 isoenzyme | - | 8.07 | pKi | 8.5 | nM | Ki | Cell Biochem Biophys (1998) 29: 113-32 [PMID:9631241] |
| phosphodiesterase 4C in Human [GtoPdb: 1302] [UniProtKB: Q08493] | ||||||||
| GtoPdb | Inhibition of [3H]-R-rolipram binding to recombinant human PDE4C2 isoenzyme | - | 7.72 | pKi | 18.9 | nM | Ki | Cell Biochem Biophys (1998) 29: 113-32 [PMID:9631241] |
| phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499] | ||||||||
| GtoPdb | Inhibition of [3H]-R-rolipram binding to recombinant human PDE4D3 isoenzyme | - | 8.15 | pKi | 7.1 | nM | Ki | Cell Biochem Biophys (1998) 29: 113-32 [PMID:9631241] |
ChEMBL data shown on this page come from version 36:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
