abediterol [Ligand Id: 9326] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL3039530 (LAS-100977, LAS100977, Abediterol)
  • β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
  • This target only has 0 pki data point
  • 0
1 CHEMBL3039530_lig_chart_1 β1-adrenoceptor Human
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  • β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
  • This target only has 0 pki data point
  • 0
2 CHEMBL3039530_lig_chart_2 β2-adrenoceptor Human
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  • β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
  • This target only has 0 pki data point
  • 0
3 CHEMBL3039530_lig_chart_3 β3-adrenoceptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
GtoPdb Membrane radioligand displacement assay using [3H]CGP12177 as tracer. - 7.44 pIC50 36.2 nM IC50 J Pharmacol Exp Ther (2012) 342: 497-509 [PMID:22588259]
β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
GtoPdb Membrane radioligand displacement assay using [3H]CGP12177 as tracer. - 9.22 pIC50 0.6 nM IC50 J Pharmacol Exp Ther (2012) 342: 497-509 [PMID:22588259]
β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
GtoPdb - - 5.52 pIC50 3001 nM IC50 J Pharmacol Exp Ther (2012) 342: 497-509 [PMID:22588259]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]