PRN694 [Ligand Id: 9285] activity data from GtoPdb

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  • BLK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 1940] [UniProtKB: P51451]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 BLK proto-oncogene, Src family tyrosine kinase Human
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  • BMX non-receptor tyrosine kinase in Human [GtoPdb: 1942] [UniProtKB: P51813]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 BMX non-receptor tyrosine kinase Human
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  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 Bruton tyrosine kinase Human
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  • IL2 inducible T cell kinase in Human [GtoPdb: 2046] [UniProtKB: Q08881]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 IL2 inducible T cell kinase Human
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  • Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
  • This target only has 0 pki data point
  • 0
5 _lig_chart_5 Janus kinase 3 Human
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  • tec protein tyrosine kinase in Human [GtoPdb: 2238] [UniProtKB: P42680]
  • This target only has 0 pki data point
  • 0
6 _lig_chart_6 tec protein tyrosine kinase Human
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  • TXK tyrosine kinase in Human [GtoPdb: 2268] [UniProtKB: P42681]
  • This target only has 0 pki data point
  • 0
7 _lig_chart_7 TXK tyrosine kinase Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BLK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 1940] [UniProtKB: P51451]
GtoPdb - - 6.9 pIC50 125 nM IC50 J Biol Chem (2015) 290: 5960-78 [PMID:25593320]
BMX non-receptor tyrosine kinase in Human [GtoPdb: 1942] [UniProtKB: P51813]
GtoPdb - - 7.77 pIC50 17 nM IC50 J Biol Chem (2015) 290: 5960-78 [PMID:25593320]
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb - - 7.77 pIC50 17 nM IC50 J Biol Chem (2015) 290: 5960-78 [PMID:25593320]
IL2 inducible T cell kinase in Human [GtoPdb: 2046] [UniProtKB: Q08881]
GtoPdb - - 9.52 pIC50 0.3 nM IC50 J Biol Chem (2015) 290: 5960-78 [PMID:25593320]
Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
GtoPdb - - 7.52 pIC50 30 nM IC50 J Biol Chem (2015) 290: 5960-78 [PMID:25593320]
tec protein tyrosine kinase in Human [GtoPdb: 2238] [UniProtKB: P42680]
GtoPdb - - 8.48 pIC50 3.3 nM IC50 J Biol Chem (2015) 290: 5960-78 [PMID:25593320]
TXK tyrosine kinase in Human [GtoPdb: 2268] [UniProtKB: P42681]
GtoPdb - - 8.85 pIC50 1.4 nM IC50 J Biol Chem (2015) 290: 5960-78 [PMID:25593320]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.