M826 [Ligand Id: 8654] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1184755 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| Caspase 1 in Human [GtoPdb: 1617] [UniProtKB: P29466] | ||||||||
| GtoPdb | - | - | 7.3 | pIC50 | 50 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 1173-80 [PMID:15686936] |
| Caspase 3 in Human [GtoPdb: 1619] [UniProtKB: P42574] | ||||||||
| GtoPdb | - | - | 8.3 | pKi | 5 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 1173-80 [PMID:15686936] |
| Caspase 4 in Human [GtoPdb: 1620] [UniProtKB: P49662] | ||||||||
| GtoPdb | - | - | 6.52 | pIC50 | 300 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 1173-80 [PMID:15686936] |
| Caspase 5 in Human [GtoPdb: 1621] [UniProtKB: P51878] | ||||||||
| GtoPdb | - | - | 6.7 | pIC50 | 200 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 1173-80 [PMID:15686936] |
| Caspase 7 in Human [GtoPdb: 1623] [UniProtKB: P55210] | ||||||||
| GtoPdb | - | - | 7.89 | pIC50 | 13 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 1173-80 [PMID:15686936] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
