ChEMBL ligand: CHEMBL3125351
Acetylcholinesterase in Electrophorus electricus [ChEMBL: CHEMBL4078] [UniProtKB: O42275] There should be some charts here, you may need to enable JavaScript!
elastase, neutrophil expressed/Leukocyte elastase in Human [ChEMBL: CHEMBL248] [GtoPdb: 2358] [UniProtKB: P08246] There should be some charts here, you may need to enable JavaScript!
coagulation factor II, thrombin/Thrombin in Human [ChEMBL: CHEMBL204] [GtoPdb: 2362] [UniProtKB: P00734] There should be some charts here, you may need to enable JavaScript!
carboxyl ester lipase in Pig [GtoPdb: 2872] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Acetylcholinesterase in Electrophorus electricus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4078] [UniProtKB: O42275]
ChEMBL	Inhibition of electric eel AChE	B	4.64	pIC50	22900	nM	IC50	Bioorg Med Chem Lett (2014) 24: 1545-1549 [PMID:24556381]
elastase, neutrophil expressed/Leukocyte elastase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL248] [GtoPdb: 2358] [UniProtKB: P08246]
GtoPdb	-	-	6.2	pIC50	630	nM	IC50	Bioorg Med Chem Lett (2014) 24: 1545-9 [PMID:24556381]
ChEMBL	Inhibition of human leukocyte elastase	B	6.2	pIC50	630	nM	IC50	Bioorg Med Chem Lett (2014) 24: 1545-1549 [PMID:24556381]
coagulation factor II, thrombin/Thrombin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL204] [GtoPdb: 2362] [UniProtKB: P00734]
ChEMBL	Inhibition of human thrombin using H-D-Phe-L-Pip-Arg-para-nitroanilide as substrate after 5 mins	B	4.52	pIC50	>=30000	nM	IC50	Bioorg Med Chem Lett (2014) 24: 1545-1549 [PMID:24556381]
carboxyl ester lipase in Pig [GtoPdb: 2872]
GtoPdb	-	-	5.7	pIC50	1980	nM	IC50	Bioorg Med Chem Lett (2014) 24: 1545-9 [PMID:24556381]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]