NG-25 [Ligand Id: 8074] activity data from GtoPdb

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  • C-terminal Src kinase in Human [GtoPdb: 1994] [UniProtKB: P41240]
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  • LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
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  • mitogen-activated protein kinase kinase kinase 7 in Human [GtoPdb: 2082] [UniProtKB: O43318]
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  • mitogen-activated protein kinase kinase kinase kinase 2 in Human [GtoPdb: 2086] [UniProtKB: Q12851]
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  • SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
C-terminal Src kinase in Human [GtoPdb: 1994] [UniProtKB: P41240]
GtoPdb - - 7.25 pIC50 56.4 nM IC50 J Med Chem (2015) 58: 183-96 [PMID:25075558]
LYN proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2060] [UniProtKB: P07948]
GtoPdb - - 7.89 pIC50 12.9 nM IC50 J Med Chem (2015) 58: 183-96 [PMID:25075558]
mitogen-activated protein kinase kinase kinase 7 in Human [GtoPdb: 2082] [UniProtKB: O43318]
GtoPdb - - 6.83 pIC50 149 nM IC50 J Med Chem (2015) 58: 183-96 [PMID:25075558]
mitogen-activated protein kinase kinase kinase kinase 2 in Human [GtoPdb: 2086] [UniProtKB: Q12851]
GtoPdb - - 7.66 pIC50 21.7 nM IC50 J Med Chem (2015) 58: 183-96 [PMID:25075558]
SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
GtoPdb - - 6.95 pIC50 113 nM IC50 J Med Chem (2015) 58: 183-96 [PMID:25075558]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.