ChEMBL ligand: CHEMBL1230065 (Bms-582949, Ps-540446, BMS-582949, PS-540446)
mitogen-activated protein kinase 14/MAP kinase p38 alpha in Human [ChEMBL: CHEMBL260] [GtoPdb: 1499] [UniProtKB: Q16539] There should be some charts here, you may need to enable JavaScript!
mitogen-activated protein kinase 11/MAP kinase p38 beta in Human [ChEMBL: CHEMBL3961] [GtoPdb: 1500] [UniProtKB: Q15759] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
mitogen-activated protein kinase 14/MAP kinase p38 alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL260] [GtoPdb: 1499] [UniProtKB: Q16539]
ChEMBL	Inhibition of bacterially expressed p38alpha pretreated for 10 mins measured after 45 mins	B	7.89	pIC50	13	nM	IC50	J. Med. Chem. (2010) 53: 6629-6639 [PMID:20804198]
ChEMBL	Inhibition of P38alpha MAPK (unknown origin)	B	7.89	pIC50	13	nM	IC50	Eur J Med Chem (2019) 182: 111624-111624 [PMID:31445234]
GtoPdb	-	-	7.89	pIC50	13	nM	IC50	J Med Chem (2010) 53: 6629-39 [PMID:20804198]
mitogen-activated protein kinase 11/MAP kinase p38 beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3961] [GtoPdb: 1500] [UniProtKB: Q15759]
ChEMBL	Inhibition of p38beta (unknown origin)	B	7.21	pIC50	62	nM	IC50	Bioorg. Med. Chem. Lett. (2013) 23: 4120-4126 [PMID:23746475]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]