L-lysine [Ligand Id: 724] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL8085 (Lysine) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| glutathione-disulfide reductase/Glutathione reductase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2755] [GtoPdb: 2613] [UniProtKB: P00390] | ||||||||
| ChEMBL | Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis | B | 4.26 | pKi | 54600 | nM | Ki | Bioorg Med Chem Lett (2011) 21: 5398-5402 [PMID:21795044] |
| ChEMBL | Inhibition of human erythrocyte Glutathione reductase | B | 4.21 | pIC50 | 61200 | nM | IC50 | Bioorg Med Chem Lett (2011) 21: 5398-5402 [PMID:21795044] |
| GPRC6 receptor in Human [GtoPdb: 55] [UniProtKB: Q5T6X5] | ||||||||
| GtoPdb | - | - | 3.8 | pEC50 | - | - | - | Mol Pharmacol (2005) 67: 589-97 [PMID:15576628] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
