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ChEMBL ligand: CHEMBL513 (BCNU, Becenun, Bicnu, Bischloroethyl nitrosourea, Camustine, Carmubris, Carmustine, DTI-015, FDA-0345, Gliadel, NSC-409962, SK-27702, SRI-1720) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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glutathione-disulfide reductase/Glutathione reductase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2755] [GtoPdb: 2613] [UniProtKB: P00390] | ||||||||
ChEMBL | Inhibition of human recombinant glutathione reductase using glutathione as substrate preincubated for 30 mins by colorimetric assay | B | 5.09 | pIC50 | 8100 | nM | IC50 | Eur. J. Med. Chem. (2014) 71: 282-289 [PMID:24321832] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]