MRS5151 [Ligand Id: 5622] activity data from GtoPdb

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  • A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
  • A1 receptor in Mouse [GtoPdb: 18] [UniProtKB: Q60612]
Created with Highcharts 10.3.3ValuesChart context menuA1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 Mouse0123456Highcharts.com
  • A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
  • A2A receptor in Mouse [GtoPdb: 19] [UniProtKB: Q60613]
Created with Highcharts 10.3.3ValuesChart context menuA2A receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 Mouse0123456Highcharts.com
  • A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
  • A3 receptor in Mouse [GtoPdb: 21] [UniProtKB: Q61618]
Created with Highcharts 10.3.3ValuesChart context menuA3 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 Mouse0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
GtoPdb - - 4.83 pKi 14900 nM Ki Bioorg Med Chem Lett (2008) 18: 2813-9 [PMID:18424135]
A1 receptor in Mouse [GtoPdb: 18] [UniProtKB: Q60612]
GtoPdb - - 4.98 pKi 10500 nM Ki Bioorg Med Chem Lett (2008) 18: 2813-9 [PMID:18424135]
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
GtoPdb - - 5 pKi >10000 nM Ki Bioorg Med Chem Lett (2008) 18: 2813-9 [PMID:18424135]
A2A receptor in Mouse [GtoPdb: 19] [UniProtKB: Q60613]
GtoPdb - - 5 pKi >10000 nM Ki Bioorg Med Chem Lett (2008) 18: 2813-9 [PMID:18424135]
A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
GtoPdb - - 8.62 pKi 2.38 nM Ki Bioorg Med Chem Lett (2008) 18: 2813-9 [PMID:18424135]
A3 receptor in Mouse [GtoPdb: 21] [UniProtKB: Q61618]
GtoPdb - - 7.61 pKi 24.4 nM Ki Bioorg Med Chem Lett (2008) 18: 2813-9 [PMID:18424135]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.