[125I]ICYP [Ligand Id: 562] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
Created with Highcharts 10.3.3ValuesChart context menuβ1-adrenoceptorpKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
Created with Highcharts 10.3.3ValuesChart context menuβ2-adrenoceptorpKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
  • β3-adrenoceptor in Mouse [GtoPdb: 30] [UniProtKB: P25962]
  • β3-adrenoceptor in Rat [GtoPdb: 30] [UniProtKB: P26255]
Created with Highcharts 10.3.3ValuesChart context menuβ3-adrenoceptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 MousepKd RatpKi RatpIC50 RatpEC50 Rat024681012Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
GtoPdb - - 11.3 pKd 0 nM Kd Eur J Pharmacol (1996) 315: 363-7 [PMID:8982677];
Eur J Pharmacol (1999) 367: 431-5 [PMID:10079020];
Mol Pharmacol (1999) 56: 875-85 [PMID:10531390];
Br J Pharmacol (2004) 142: 51-6 [PMID:15037517]
β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
GtoPdb - - 11.4 pKd 0.01 nM Kd Eur J Pharmacol (1996) 315: 363-7 [PMID:8982677];
Eur J Pharmacol (1999) 367: 431-5 [PMID:10079020];
Br J Pharmacol (2012) 165: 2672-83 [PMID:21883146]
β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
GtoPdb - - 9.8 pKd 0.16 nM Kd Eur J Pharmacol (1996) 315: 363-7 [PMID:8982677];
Eur J Pharmacol (1999) 367: 431-5 [PMID:10079020];
Annu Rev Pharmacol Toxicol (1997) 37: 421-50 [PMID:9131260];
Br J Pharmacol (1997) 120: 165-76 [PMID:9117106];
Eur J Pharmacol (2004) 484: 323-31 [PMID:14744619]
β3-adrenoceptor in Mouse [GtoPdb: 30] [UniProtKB: P25962]
GtoPdb - - 9.4 pKd - - - Eur J Pharmacol (2004) 484: 323-31 [PMID:14744619]
β3-adrenoceptor in Rat [GtoPdb: 30] [UniProtKB: P26255]
GtoPdb - - 9.2 pKd - - - Eur J Pharmacol (2004) 484: 323-31 [PMID:14744619]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.