cordycepin [Ligand Id: 4630] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL305686 (3'-Deoxyadenosine, 9-cordyceposidoadenine, Cordycepin, Cordycepine, NSC-401022, NSC-63984) |
|---|
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| A1 receptor/Adenosine A1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL318] [GtoPdb: 18] [UniProtKB: P25099] | ||||||||
| ChEMBL | Affinity for the Adenosine A1 receptor in the presence of GTP (A1+GTP) by using [3H]-DPCPX as radioligand | B | 4.82 | pKi | 15200 | nM | Ki | J Med Chem (1995) 38: 4000-4006 [PMID:7562934] |
| ChEMBL | Affinity for adenosine A1 receptor was determined, in the presence of GTP in rat brain cortex | B | 4.82 | pKi | 15200 | nM | Ki | J Med Chem (1997) 40: 3765-3772 [PMID:9371242] |
| ChEMBL | Affinity for the Adenosine A1 receptor in the absence of GTP (A1-GTP) by using [3H]DPCPX as radioligand | B | 5.15 | pKi | 7120 | nM | Ki | J Med Chem (1995) 38: 4000-4006 [PMID:7562934] |
| ChEMBL | Affinity for adenosine A1 receptor was determined, in the absence of GTP in rat cortical membrane. | B | 5.15 | pKi | 7120 | nM | Ki | J Med Chem (1997) 40: 3765-3772 [PMID:9371242] |
| Hepatitis C virus NS5B RNA-dependent RNA polymerase in Hepatitis C virus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5375] [UniProtKB: Q8JXU8] | ||||||||
| ChEMBL | Inhibition HCV NS5B-mediated RNA synthesis | F | 4.66 | pIC50 | 22000 | nM | IC50 | J Med Chem (2004) 47: 2283-2295 [PMID:15084127] |
| ChEMBL | Inhibition HCV RNA replication | F | 4.34 | pEC50 | 46000 | nM | EC50 | J Med Chem (2004) 47: 2283-2295 [PMID:15084127] |
| Sterol 14-alpha demethylase in Trypanosoma cruzi (strain CL Brener) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075110] [UniProtKB: Q7Z1V1] | ||||||||
| ChEMBL | GSK_TCAKS: pIC50 CYP51 from Trypanosoma cruzi. | F | 4 | pIC50 | >100000 | nM | IC50 | GSK Tres Cantos Anti-Kinetoplastid Screening (TCAKS) Data. |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
