ChEMBL ligand: CHEMBL17002
A1 receptor/Adenosine A1 receptor in Human [ChEMBL: CHEMBL226] [GtoPdb: 18] [UniProtKB: P30542] A1 receptor/Adenosine A1 receptor in Rat [ChEMBL: CHEMBL318] [GtoPdb: 18] [UniProtKB: P25099] There should be some charts here, you may need to enable JavaScript!
A2A receptor/Adenosine A2a receptor in Human [ChEMBL: CHEMBL251] [GtoPdb: 19] [UniProtKB: P29274] A2A receptor/Adenosine A2a receptor in Rat [ChEMBL: CHEMBL302] [GtoPdb: 19] [UniProtKB: P30543] There should be some charts here, you may need to enable JavaScript!
A2B receptor/Adenosine A2b receptor in Human [ChEMBL: CHEMBL255] [GtoPdb: 20] [UniProtKB: P29275] There should be some charts here, you may need to enable JavaScript!
A3 receptor/Adenosine A3 receptor in Human [ChEMBL: CHEMBL256] [GtoPdb: 21] [UniProtKB: P0DMS8] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
A1 receptor/Adenosine A1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL226] [GtoPdb: 18] [UniProtKB: P30542]
ChEMBL	Antagonist activity against recombinant human adenosine A1 receptor expressed in HEK293 cells in presence of [125I]IABA radioligand.	F	6.8	pKi	157	nM	Ki	J. Med. Chem. (2000) 43: 1165-1172 [PMID:10737749]
ChEMBL	Antagonist activity against human adenosine A1 receptor	F	6.8	pKi	157	nM	Ki	Eur. J. Med. Chem. (2010) 45: 3459-3471 [PMID:20537438]
A1 receptor/Adenosine A1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL318] [GtoPdb: 18] [UniProtKB: P25099]
ChEMBL	Antagonist activity against adenosine A1 receptor in rat brain membrane in presence of [3H]R-PIA radioligand.	F	7.42	pKi	37.6	nM	Ki	J. Med. Chem. (2000) 43: 1165-1172 [PMID:10737749]
A2A receptor/Adenosine A2a receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL251] [GtoPdb: 19] [UniProtKB: P29274]
ChEMBL	Antagonist activity against recombinant human adenosine A2A receptor expressed in HEK293 cells in presence of [125I]iodo-ZM-241385 radioligand.	F	6.95	pKi	112	nM	Ki	J. Med. Chem. (2000) 43: 1165-1172 [PMID:10737749]
ChEMBL	Antagonist activity against human adenosine A2A receptor	F	6.95	pKi	112	nM	Ki	Eur. J. Med. Chem. (2010) 45: 3459-3471 [PMID:20537438]
A2A receptor/Adenosine A2a receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL302] [GtoPdb: 19] [UniProtKB: P30543]
ChEMBL	Antagonist activity against adenosine A2A receptor in rat striatal membrane in presence of [3H]CGS-21680 radioligand.	F	6.26	pKi	548	nM	Ki	J. Med. Chem. (2000) 43: 1165-1172 [PMID:10737749]
A2B receptor/Adenosine A2b receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL255] [GtoPdb: 20] [UniProtKB: P29275]
ChEMBL	Antagonist activity against human A2B adenosine receptor expressed in HEK293 cells uisng [3H]ZM-241385 or [125I]-IABOPX	F	8.86	pKi	1.39	nM	Ki	J. Med. Chem. (2000) 43: 1165-1172 [PMID:10737749]
ChEMBL	Antagonist activity against human adenosine A2B receptor	F	8.86	pKi	1.39	nM	Ki	Eur. J. Med. Chem. (2010) 45: 3459-3471 [PMID:20537438]
A3 receptor/Adenosine A3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL256] [GtoPdb: 21] [UniProtKB: P0DMS8]
ChEMBL	Antagonist activity against human adenosine A3 receptor expressed in HEK cells in presence of [125]IAB-MECA or [125I]IABA radioligand.	F	6.64	pKi	230	nM	Ki	J. Med. Chem. (2000) 43: 1165-1172 [PMID:10737749]
ChEMBL	Antagonist activity against human adenosine A3 receptor	F	6.64	pKi	230	nM	Ki	Eur. J. Med. Chem. (2010) 45: 3459-3471 [PMID:20537438]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]