gentamicin [Ligand Id: 2427] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL329592
  • TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
Created with Highcharts 10.3.3ValuesChart context menuTRPA1pKd MousepKi MousepIC50 MousepEC50 Mouse0123456Highcharts.com
  • TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5]
Created with Highcharts 10.3.3ValuesChart context menuTRPV5pKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb - - 5.2 pIC50 - - - J Neurosci (2005) 25: 4052-61 [PMID:15843607]
TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5]
GtoPdb - - 6 pIC50 1000 nM IC50 J Am Soc Nephrol (2022) 33: 547-564 [PMID:35022312]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]