zilurgisertib [Ligand Id: 11888] activity data from GtoPdb

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  • activin A receptor type IL in Human [GtoPdb: 1784] [UniProtKB: P37023]
Created with Highcharts 10.3.3ValuesChart context menuactivin A receptor type ILpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • activin A receptor type 1 in Human [GtoPdb: 1785] [UniProtKB: Q04771]
Created with Highcharts 10.3.3ValuesChart context menuactivin A receptor type 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • bone morphogenetic protein receptor type IA in Human [GtoPdb: 1786] [UniProtKB: P36894]
Created with Highcharts 10.3.3ValuesChart context menubone morphogenetic protein receptor type IApKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
  • transforming growth factor beta receptor 1 in Human [GtoPdb: 1788] [UniProtKB: P36897]
Created with Highcharts 10.3.3ValuesChart context menutransforming growth factor beta receptor 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
  • bone morphogenetic protein receptor type IB in Human [GtoPdb: 1789] [UniProtKB: O00238]
Created with Highcharts 10.3.3ValuesChart context menubone morphogenetic protein receptor type IBpKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
activin A receptor type IL in Human [GtoPdb: 1784] [UniProtKB: P37023]
GtoPdb - - 6.49 pIC50 323 nM IC50 US20210155606A1. Aminopyridine derivatives and their use as selective alk-2 inhibitors (2021)
activin A receptor type 1 in Human [GtoPdb: 1785] [UniProtKB: Q04771]
GtoPdb - - 7.64 pIC50 23 nM IC50 US20210155606A1. Aminopyridine derivatives and their use as selective alk-2 inhibitors (2021)
bone morphogenetic protein receptor type IA in Human [GtoPdb: 1786] [UniProtKB: P36894]
GtoPdb - - 6.04 pIC50 914 nM IC50 US20210155606A1. Aminopyridine derivatives and their use as selective alk-2 inhibitors (2021)
transforming growth factor beta receptor 1 in Human [GtoPdb: 1788] [UniProtKB: P36897]
GtoPdb - - 5.2 pIC50 6280 nM IC50 US20210155606A1. Aminopyridine derivatives and their use as selective alk-2 inhibitors (2021)
bone morphogenetic protein receptor type IB in Human [GtoPdb: 1789] [UniProtKB: O00238]
GtoPdb - - 5.48 pIC50 3300 nM IC50 US20210155606A1. Aminopyridine derivatives and their use as selective alk-2 inhibitors (2021)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.