tanuxiciclib [Ligand Id: 11885] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| cyclin dependent kinase 1 in Human [GtoPdb: 1961] [UniProtKB: P06493] | ||||||||
| GtoPdb | CDK1/cyclinD1 | - | 9.22 | pIC50 | 0.6 | nM | IC50 | WO2016126085A2. Heterocyclic compound and pharmaceutical composition comprising same (2016) |
| cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941] | ||||||||
| GtoPdb | CDK2/cyclinE | - | 9.05 | pIC50 | 0.9 | nM | IC50 | WO2016126085A2. Heterocyclic compound and pharmaceutical composition comprising same (2016) |
| cyclin dependent kinase 4 in Human [GtoPdb: 1976] [UniProtKB: P11802] | ||||||||
| GtoPdb | CDK3/cyclinD | - | 6.47 | pIC50 | 341.5 | nM | IC50 | WO2016126085A2. Heterocyclic compound and pharmaceutical composition comprising same (2016) |
| cyclin dependent kinase 5 in Human [GtoPdb: 1977] [UniProtKB: Q00535] | ||||||||
| GtoPdb | CDK5/p25 | - | 9.15 | pIC50 | 0.7 | nM | IC50 | WO2016126085A2. Heterocyclic compound and pharmaceutical composition comprising same (2016) |
| cyclin dependent kinase 6 in Human [GtoPdb: 1978] [UniProtKB: Q00534] | ||||||||
| GtoPdb | CDK6/cyclinD | - | 7.47 | pIC50 | 33.8 | nM | IC50 | WO2016126085A2. Heterocyclic compound and pharmaceutical composition comprising same (2016) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
