ABD-1970 [Ligand Id: 11816] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL4517565 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| monoacylglycerol lipase in Human [GtoPdb: 1399] [UniProtKB: Q99685] | ||||||||
| GtoPdb | hMAGL from PC3 cell lysate | - | 7.74 | pIC50 | 18 | nM | IC50 | J Pharmacol Exp Ther (2018) 367: 494-508 [PMID:30305428] |
| monoacylglycerol lipase in Mouse [GtoPdb: 1399] [UniProtKB: O35678] | ||||||||
| GtoPdb | MAGL in mouse brain | - | 7.82 | pIC50 | 15 | nM | IC50 | J Pharmacol Exp Ther (2018) 367: 494-508 [PMID:30305428] |
| monoacylglycerol lipase in Rat [GtoPdb: 1399] [UniProtKB: Q8R431] | ||||||||
| GtoPdb | MAGL in rat brain cortex | - | 8.52 | pIC50 | 3 | nM | IC50 | J Pharmacol Exp Ther (2018) 367: 494-508 [PMID:30305428] |
| αβ-Hydrolase 6 in Mouse [GtoPdb: 2919] [UniProtKB: Q8R2Y0] | ||||||||
| GtoPdb | - | - | 5.49 | pIC50 | 3200 | nM | IC50 | J Pharmacol Exp Ther (2018) 367: 494-508 [PMID:30305428] |
| αβ-Hydrolase 6 in Rat [GtoPdb: 2919] [UniProtKB: Q5XI64] | ||||||||
| GtoPdb | - | - | 6.1 | pIC50 | 800 | nM | IC50 | J Pharmacol Exp Ther (2018) 367: 494-508 [PMID:30305428] |
ChEMBL data shown on this page come from version 36:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
