AZD4635 [Ligand Id: 11153] activity data from GtoPdb

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  • A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
  • This target only has 1 pki data point
  • 6.8
1 _lig_chart_1 A1 receptor Human
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  • A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
  • This target only has 1 pki data point
  • 8.77
2 _lig_chart_2 A2A receptor Human
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  • A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
  • This target only has 1 pki data point
  • 7.19
3 _lig_chart_3 A2B receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
GtoPdb Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from CHO cells stably expressing human A1R. - 6.8 pKi 160 nM Ki J Immunother Cancer (2020) 8: e000417 [PMID:32727810]
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
GtoPdb Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from HEK-293-T cells stably expressing human A2AR. - 8.77 pKi 1.7 nM Ki J Immunother Cancer (2020) 8: e000417 [PMID:32727810]
A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
GtoPdb Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from HEK-293-T cells stably expressing human A2BR. - 7.19 pKi 64 nM Ki J Immunother Cancer (2020) 8: e000417 [PMID:32727810]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.