Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
1
_lig_chart_1
A1 receptor
Human
There should be some charts here, you may need to enable JavaScript!
|
2
_lig_chart_2
A2A receptor
Human
There should be some charts here, you may need to enable JavaScript!
|
3
_lig_chart_3
A2B receptor
Human
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542] | ||||||||
GtoPdb | Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from CHO cells stably expressing human A1R. | - | 6.8 | pKi | 160 | nM | Ki | J Immunother Cancer (2020) 8: e000417 [PMID:32727810] |
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274] | ||||||||
GtoPdb | Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from HEK-293-T cells stably expressing human A2AR. | - | 8.77 | pKi | 1.7 | nM | Ki | J Immunother Cancer (2020) 8: e000417 [PMID:32727810] |
A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275] | ||||||||
GtoPdb | Binding affinity of AZD4635 determined in a radioligand binding competition assays with membranes prepared from HEK-293-T cells stably expressing human A2BR. | - | 7.19 | pKi | 64 | nM | Ki | J Immunother Cancer (2020) 8: e000417 [PMID:32727810] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.