compound 41 [PMID: 31855425] [Ligand Id: 10598] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| phosphatidylinositol 3-kinase catalytic subunit type 3 in Human [GtoPdb: 2152] [UniProtKB: Q8NEB9] | ||||||||
| GtoPdb | Apparent binding affinity determined using the lipid kinobead assay. | - | 7.2 | pKd | 63.1 | nM | Kd | J Med Chem (2020) 63: 638-655 [PMID:31855425] |
| GtoPdb | Determined in a chemoproteomic competition binding assay with antibody-based readout. | - | 7.2 | pIC50 | 63.1 | nM | IC50 | J Med Chem (2020) 63: 638-655 [PMID:31855425] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336] | ||||||||
| GtoPdb | - | - | 5.8 | pIC50 | 1585 | nM | IC50 | J Med Chem (2020) 63: 638-655 [PMID:31855425] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338] | ||||||||
| GtoPdb | - | - | 5.7 | pIC50 | 1995 | nM | IC50 | J Med Chem (2020) 63: 638-655 [PMID:31855425] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329] | ||||||||
| GtoPdb | Apparent binding affinity determined using the lipid kinobead assay. | - | 9.7 | pKd | 0.2 | nM | Kd | J Med Chem (2020) 63: 638-655 [PMID:31855425] |
| GtoPdb | - | - | 8.2 | pIC50 | 6.31 | nM | IC50 | J Med Chem (2020) 63: 638-655 [PMID:31855425] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736] | ||||||||
| GtoPdb | - | - | 6.5 | pIC50 | 316 | nM | IC50 | J Med Chem (2020) 63: 638-655 [PMID:31855425] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
