compound 7 [PMID: 31381331] [Ligand Id: 10450] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| integrin, beta 1 subunit (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) in Human [GtoPdb: 2455] [UniProtKB: P05556] | ||||||||
| GtoPdb | Ki estimated from the binding affinity of the test compound to αvβ6 integrin in a radioligand binding assay. | - | 7.7 | pKi | 20 | nM | Ki | J Med Chem (2019) 62: 7543-7556 [PMID:31381331] |
| integrin, beta 3 subunit (platelet glycoprotein IIIa, antigen CD61) in Human [GtoPdb: 2457] [UniProtKB: P05106] | ||||||||
| GtoPdb | Ki estimated from the binding affinity of the test compound to αvβ6 integrin in a radioligand binding assay. | - | 6.8 | pKi | 158 | nM | Ki | J Med Chem (2019) 62: 7543-7556 [PMID:31381331] |
| integrin, beta 5 subunit in Human [GtoPdb: 2459] [UniProtKB: P18084] | ||||||||
| GtoPdb | Ki estimated from the binding affinity of the test compound to αvβ6 integrin in a radioligand binding assay. | - | 7.3 | pKi | 50.1 | nM | Ki | J Med Chem (2019) 62: 7543-7556 [PMID:31381331] |
| integrin, beta 6 subunit in Human [GtoPdb: 2460] [UniProtKB: P18564] | ||||||||
| GtoPdb | Determined in a radioligand binding assay. | - | 9.97 | pKi | 0.11 | nM | Ki | J Med Chem (2019) 62: 7543-7556 [PMID:31381331] |
| integrin, beta 8 subunit in Human [GtoPdb: 2462] [UniProtKB: P26012] | ||||||||
| GtoPdb | Ki estimated from the binding affinity of the test compound to αvβ6 integrin in a radioligand binding assay. | - | 7.6 | pKi | 25.1 | nM | Ki | J Med Chem (2019) 62: 7543-7556 [PMID:31381331] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
