LUF7602 [Ligand Id: 10351] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542] | ||||||||
| GtoPdb | Affinity determined from the displacement of specific [3H]DPCPX binding on CHO cell membranes stably expressing human adenosine A1 receptors at 25 °C during 2 h of incubation. | - | 6.1 | pKi | 794 | nM | Ki | J Med Chem (2019) 62: 3539-3552 [PMID:30869893] |
| A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274] | ||||||||
| GtoPdb | Affinity determined from the displacement of specific [3H]ZM241385 binding on HEK293 cell membranes stably expressing human adenosine A2A receptors at 25 °C during 2 h of incubation. | - | 5.9 | pKi | 1259 | nM | Ki | J Med Chem (2019) 62: 3539-3552 [PMID:30869893] |
| A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8] | ||||||||
| GtoPdb | Displacement of [3H]PSB-11 binding from the hA3AR (in membranes from stably transfected CHO cells) following preincubation for 4 h, | - | 8 | pKi | 10 | nM | Ki | J Med Chem (2019) 62: 3539-3552 [PMID:30869893] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
