phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336] There should be some charts here, you may need to enable JavaScript!
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338] There should be some charts here, you may need to enable JavaScript!
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329] There should be some charts here, you may need to enable JavaScript!
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
GtoPdb	-	-	5.4	pIC50	3981	nM	IC50	Nat Chem Biol (2019) 15: 348-357 [PMID:30718815]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
GtoPdb	-	-	4.5	pIC50	31622	nM	IC50	Nat Chem Biol (2019) 15: 348-357 [PMID:30718815]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
GtoPdb	-	-	6.7	pKi	199	nM	Ki	Nat Chem Biol (2019) 15: 348-357 [PMID:30718815]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
GtoPdb	Binding affinity determined by SPR using a two-step binding model.	-	8.65	pKd	2.24	nM	Kd	Nat Chem Biol (2019) 15: 348-357 [PMID:30718815]
GtoPdb	Biochemical assay using purified protein expressed from a construct containing C-terminal 6-His-tagged human p110&gamma (S144-A1102).	-	9.46	pIC50	0.35	nM	IC50	Nat Chem Biol (2019) 15: 348-357 [PMID:30718815]