AM-6120 [Ligand Id: 10119] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Nav1.4 in Human [GtoPdb: 581] [UniProtKB: P35499] | ||||||||
| GtoPdb | Determined in a PatchXpress electrophysiology experiment using HEK293 cells stably expressing hNaV1.4. | - | 6.98 | pIC50 | 104 | nM | IC50 | J Med Chem (2018) 61: 9500-9512 [PMID:30346167] |
| Nav1.5 in Human [GtoPdb: 582] [UniProtKB: Q14524] | ||||||||
| GtoPdb | Determined in a PatchXpress electrophysiology experiment using HEK293 cells stably expressing hNaV1.5. | - | 5.18 | pIC50 | 6640 | nM | IC50 | J Med Chem (2018) 61: 9500-9512 [PMID:30346167] |
| Nav1.6 in Human [GtoPdb: 583] [UniProtKB: Q9UQD0] | ||||||||
| GtoPdb | Determined in a PatchXpress electrophysiology experiment using HEK293 cells stably expressing hNaV1.6. | - | 6.22 | pIC50 | 604 | nM | IC50 | J Med Chem (2018) 61: 9500-9512 [PMID:30346167] |
| Nav1.7 in Human [GtoPdb: 584] [UniProtKB: Q15858] | ||||||||
| GtoPdb | Determined in a PatchXpress electrophysiology experiment using HEK293 cells stably expressing hNaV1.7. | - | 9.1 | pIC50 | 0.8 | nM | IC50 | J Med Chem (2018) 61: 9500-9512 [PMID:30346167] |
| Nav1.7 in Mouse [GtoPdb: 584] [UniProtKB: Q62205] | ||||||||
| GtoPdb | Determined in a PatchXpress electrophysiology experiment using HEK293 cells stably expressing mNaV1.7. | - | 8.27 | pIC50 | 5.4 | nM | IC50 | J Med Chem (2018) 61: 9500-9512 [PMID:30346167] |
| Nav1.8 in Human [GtoPdb: 585] [UniProtKB: Q9Y5Y9] | ||||||||
| GtoPdb | Determined in a PatchXpress electrophysiology experiment using HEK293 cells stably expressing hNaV1.8. | - | 6 | pIC50 | >1000 | nM | IC50 | J Med Chem (2018) 61: 9500-9512 [PMID:30346167] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
